The Hoffner Historic District is a historic collection of buildings in the Northside neighborhood of Cincinnati, Ohio, United States. Built primarily at the end of the nineteenth century, the district has experienced few changes since it was built, and it has been named a historic site.

It is composed of twelve buildings in an area of 5 acres (2.0 ha), of which eleven contribute to its historic nature. The buildings are four commercial buildings along Hamilton Avenue, including the Hoffner Lodge at the corner; six small private residences on Moline Court; and the Myron Johnson Lumber Company building behind them on Langland Street. The southern portion of the block was in the 1970s occupied by a non-contributing gas station, which has since been replaced with a new apartment complex.